478258-81-0

Usage

Uses

Used in Pharmaceutical Industry:
5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE is used as a key intermediate in the synthesis of drugs for various therapeutic applications, including anti-cancer and anti-inflammatory properties. Its unique structure allows for the development of novel compounds with potential medicinal properties.
Used in Agrochemical Industry:
5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE is used as a building block in the synthesis of agrochemicals, contributing to the development of new pesticides, herbicides, and other agricultural chemicals to improve crop protection and yield.
Used in Organic Synthesis:
5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE is used as a versatile starting material in organic synthesis for the preparation of complex molecules. Its presence of a bromine atom and pyrrole ring enables the formation of diverse chemical structures with potential applications in various fields.
Overall, 5-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyrimidine is a valuable chemical compound with diverse potential applications in the field of drug discovery, agrochemical development, and organic synthesis, making it an essential component in the advancement of various industries.

InChI:InChI=1/C10H10BrN3/c1-7-3-4-8(2)14(7)10-12-5-9(11)6-13-10/h3-6H,1-2H3

Upstream product

• 7752-82-1 5-bromo-2-aminopyrimidine 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 1011300-79-0 6-{1-[4-[2-(2,5-dimethyl-1H-pyrrol-1-yl)pyrimidin-5-yl]phenyl]-1,2-dimethylpropyl}pyridin-3-ol 
• 1083329-35-4 2-N-(2,5-dimethylpyrrolo)-5-benzyloxypyrimidine 

Relevant academic research and scientific papers

Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis

Herein we report an investigation of the efficacy of pyridine and pyrimidine analogs of acetaminophen (ApAP) as peroxyl radical-trapping antioxidants and inhibitors of enzyme-catalyzed lipid peroxidation by cyclooxygenases (COX) and lipoxygenases (LOX). I

DIPHENYL SUBSTITUTED CYCLOALKANES

The present invention provides compounds of Formula I which are FLAP inhibitors useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

A simple Cu-catalyzed coupling approach to substituted 3-pyridinol and 5-pyrimidinol antioxidants

(Chemical Equation Presented) A convenient approach to 3-pyridinols and 5-pyrimidinols via a two-step Cu-catalyzed benzyloxylation/catalytic hydrogenation sequence is presented. The corresponding 3-pyridinamines and 5-pyrimidinamines can be prepared in an analogous sequence utilizing benzylamine in lieu of benzyl alcohol. The radical-scavenging ability of these derivatives are preliminarily explored and reveal that the increased acidities of the pyridinols and pyrimidinols render them susceptible to more significant kinetic solvent effects when compared to phenols.

DIPHENYL SUBSTITUTED ALKANES

The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors: formula (I). Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

DIARYL SUBSTITUTED ALKANES

The instant invention provides compounds of Formula (II) which are 5-lipoxygenase activating protein inhibitors. Compounds of Formula (II) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.