478374-59-3

Basic information

• Product Name: {4'-[3-(4-Ethoxyphenyl)-2-propynyloxy]biphenyl-3-yl}acetic acid
• Synonyms: {4'-[3-(4-Ethoxyphenyl)-2-propynyloxy]biphenyl-3-yl}acetic acid
• CAS NO: 478374-59-3
• Molecular Weight: 386.447
• Mol File: 478374-59-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {4'-[3-(4-Ethoxyphenyl)-2-propynyloxy]biphenyl-3-yl}acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: {4'-[3-(4-Ethoxyphenyl)-2-propynyloxy]biphenyl-3-yl}acetic acid(478374-59-3)
• EPA Substance Registry System: {4'-[3-(4-Ethoxyphenyl)-2-propynyloxy]biphenyl-3-yl}acetic acid(478374-59-3)

Safety Data

• Hazardous Substances Data: 478374-59-3(Hazardous Substances Data)

Upstream product

• 699-08-1 1-ethoxy-4-iodobenzene 

Relevant articles and documents

CARBOXYLIC ACID DERIVATIVE AND MEDICINE COMPRISING SALT OR ESTER OF THE SAME

The present invention provides novel carboxylic acid derivatives useful as an insulin sensitizer, a salt thereof or a hydrate of them, and a medicament comprising the derivative as the active ingredient. Specifically, it provides a carboxylic acid derivative represented by the following formula: (wherein L represents a single bond, or a C1 to C6 alkylene group, a C2 to C6 alkenylene group or a C2 to C6 alkynylene group, each of which may have one or more substituent groups; M represents a single bond, or a C1 to C6 alkylene group, a C2 to C6 alkenylene group or a C2 to C6 alkynylene group, each of which may have one or more substituent groups; T represents a single bond, or a C1 to C3 alkylene group, a C2 to C3 alkenylene group or a C2 to C3 alkynylene group, each of which may have one or more substituent groups; W represents a carboxyl group; X represents a single bond, an oxygen atom, or a group represented by the various substituent groups including -NRX1CQ1O- (wherein Q1 represents an oxygen atom or a sulfur atom; RX1 represents a hydrogen atom, a cyano group, a formyl group, or various groups including a C1 to C6 alkyl group and a C1 to C6 hydroxyalkyl group, each of which may have one or more substituent groups) , ONRX1CQ1-, -NRX1CQ1-, -CQ1NRX1-, -NRX1aCQ1NRX1b-, -Q2SO2- and -SO2Q2-; Y represents a 5 to 14-membered aromatic group which may have one or more substituent groups and one or more hetero atoms, or a C3 to C7 alicyclic hydrocarbon group; and the rings Z and U may be the same as or different from each other and each represents a 5 to 14-membered aromatic group which may have 1 to 4 substituent groups and one or more hetero atoms, and the ring may be partially saturated.), a salt thereof, an ester thereof or a hydrate of them.