Cas 478400-72-5,N-([1,1'-biphenyl]-3-yl)-2-(4-hydroxy-3-methoxyphenyl)acetamide

478400-72-5

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Basic information

Product Name: N-([1,1'-biphenyl]-3-yl)-2-(4-hydroxy-3-methoxyphenyl)acetamide
Synonyms: N-([1,1'-biphenyl]-3-yl)-2-(4-hydroxy-3-methoxyphenyl)acetamide
CAS NO:478400-72-5
Molecular Formula:
Molecular Weight: 333.387
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-([1,1'-biphenyl]-3-yl)-2-(4-hydroxy-3-methoxyphenyl)acetamide(CAS DataBase Reference)
NIST Chemistry Reference: N-([1,1'-biphenyl]-3-yl)-2-(4-hydroxy-3-methoxyphenyl)acetamide(478400-72-5)
EPA Substance Registry System: N-([1,1'-biphenyl]-3-yl)-2-(4-hydroxy-3-methoxyphenyl)acetamide(478400-72-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 478400-72-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 478400-72-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,4,0 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 478400-72:
(8*4)+(7*7)+(6*8)+(5*4)+(4*0)+(3*0)+(2*7)+(1*2)=165
165 % 10 = 5
So 478400-72-5 is a valid CAS Registry Number.

478400-72-5Upstream product

478400-72-5Downstream Products

478400-72-5Relevant academic research and scientific papers

Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor

Wu, Zining,Graybill, Todd L.,Zeng, Xin,Platchek, Michael,Zhang, Jean,Bodmer, Vera Q.,Wisnoski, David D.,Deng, Jianghe,Coppo, Frank T.,Yao, Gang,Tamburino, Alex,Scavello, Genaro,Franklin, G. Joseph,Mataruse, Sibongile,Bedard, Katie L.,Ding, Yun,Chai, Jing,Summerfield, Jennifer,Centrella, Paolo A.,Messer, Jeffrey A.,Pope, Andrew J.,Israel, David I.

, p. 722 - 731 (2015)

DNA-encoded small-molecule library technology has recently emerged as a new paradigm for identifying ligands against drug targets. To date, this technology has been used with soluble protein targets that are produced and used in a purified state. Here, we describe a cell-based method for identifying small-molecule ligands from DNA-encoded libraries against integral membrane protein targets. We use this method to identify novel, potent, and specific inhibitors of NK3, a member of the tachykinin family of G-protein coupled receptors (GPCRs). The method is simple and broadly applicable to other GPCRs and integral membrane proteins. We have extended the application of DNA-encoded library technology to membrane-associated targets and demonstrate the feasibility of selecting DNA-tagged, small-molecule ligands from complex combinatorial libraries against targets in a heterogeneous milieu, such as the surface of a cell.

N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME

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Page 36, (2010/02/06)

N-Arylphenylacetamide derivatives represented by the following formula [I]: (wherein R1 is C1-6 alkoxy, etc.; R2 is hydrogen, -(CH2)m-N(R6)(R7) (m is an integer of from 1 to 4; R

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