4785-52-8

Basic information

• Product Name: Benzoic acid, 5-bromo-2-formyl-
• CAS NO: 4785-52-8
• Molecular Formula: C8H5BrO3
• Molecular Weight: 229.03
• Mol File: 4785-52-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 5-bromo-2-formyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 5-bromo-2-formyl-(4785-52-8)
• EPA Substance Registry System: Benzoic acid, 5-bromo-2-formyl-(4785-52-8)

Safety Data

• Hazardous Substances Data: 4785-52-8(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 5-bromo-2-formyl- is a chemical compound with the molecular formula C8H5BrO3. It is a derivative of benzoic acid, which is commonly used as a food preservative and for its antifungal and antibacterial properties. The 5-bromo-2-formyl- substitution in this compound adds a bromine atom and a formyl group to the benzoic acid structure, potentially changing its reactivity and biological activity. Benzoic acid, 5-bromo-2-formyl- may be used in organic synthesis as a building block or intermediate for the preparation of other chemical compounds. Its properties and potential applications in various fields make it a subject of interest for research and development.

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 1016163-89-5 methyl 5-bromo-2- formylbenzoate 
• 64169-34-2 5-bromophthalide 
• 610-93-5 6-nitrophthalide 
• 19477-73-7 6-bromophthalide 
• 57319-65-0 6-aminophthalide 
• 40125-50-6 3,6-dibromo-2-benzofuran-1(3H)-one 

Downstream Products

• 38917-90-7 (±)-6-bromo-3-(4-bromophenyl)isobenzofuran-1(3H)-one 
• 1240500-28-0 5-bromo-2-[(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid 
• 1240500-32-6 N-(4-methylphenyl)-7-bromo-1-oxo-1H-isothiochromene-3-carboxamide 
• 1460036-41-2 2,5-dioxopyrrolidin-1-yl 4-{[2-(dimethylcarbamoyl)-4-phenylphenyl]methyl}piperazine-1-carboxylate 
• 871502-88-4 5-bromo-2-bis(5-methyl-2-furyl)methylbenzoic acid 
• 1446818-35-4 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[[2-(dimethylcarbamoyl)-4-phenylphenyl]methyl]piperazine-1-carboxylate 
• 1446819-61-9 N,N-dimethyl-5-phenyl-2-(piperazin-1-ylmethyl)benzamide 
• 1446819-60-8 tert-butyl 4-[[2-(dimethylcarbamoyl)-4-phenylphenyl]methyl]piperazine-1-carboxylate 
• 1446819-59-5 tert-butyl 4-[[4-bromo-2-(dimethylcarbamoyl)phenyl]methyl]piperazine-1-carboxylate 
• 1016163-89-5 methyl 5-bromo-2- formylbenzoate 

Relevant articles and documents

Synthesis of 3-Benzylphthalide Derivatives by Using a TDAE Strategy

A one-pot synthesis of new 3-benzylphthalide derivatives was developed by using a strategy based on tetrakis(dimethylamino)ethylene (TDAE). The reactions in the presence of TDAE of substituted benzyl chlorides with methyl 2-formylbenzoate or of substitute

Facile construction of pyrrolo[1,2-: B] isoquinolin-10(5 H)-ones via a redox-amination-aromatization-Friedel-Crafts acylation cascade reaction and discovery of novel topoisomerase inhibitors

An efficient redox-amination-aromatization-Friedel-Crafts acylation cascade process from trans-4-hydroxyproline and 2-formylbenzoic acids has been developed for the synthesis of pyrrolo[1,2-b]isoquinolin-10(5H)-ones. Compound 3h was identified as a new potent dual topoisomerase I/II inhibitor.

A general catalytic route to isoindolinones and tetrahydroisoquinolines: Application in the synthesis of (±)-crispine A

An unprecedented highly efficient Lewis acid catalyzed one-pot cascade has been demonstrated as a general catalytic system for the synthesis of diversely substituted isoindolinones and tetrahydroisoquinolines. The cascade effects one C-C and two C-N bond-