478501-26-7

Upstream product

• 694-80-4 2-bromo-1-chlorobenzene 
• 625-95-6 3-Iodotoluene 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 15946-36-8 2-chlorobenzenesulfinic acid sodium salt 
• 768-60-5 4-methoxyphenylacetylen 
• 2905-23-9 2-chlorophenylsulfonyl chloride 
• 615-41-8 2-iodochlorobenzene 
• 696-62-8 para-iodoanisole 
• 873-31-4 2-chlorophenylacetylene 

Downstream Products

• 1172603-16-5 1-(1-adamantyl)-2-(4-methoxyphenyl)-1H-indole 
• 1445990-36-2 5-(4-methoxyphenyl)-10-phenylindeno[2,1-a]indene 
• 1445990-44-2 10-(4-methoxyphenyl)-2-methyl-5-(p-tolyl)indeno[2,1-a]indene 
• 1445990-46-4 2-methoxy-5,10-bis(4-methoxyphenyl)indeno[2,1-a]indene 
• 1445990-49-7 5-(4-cyanophenyl)-10-(4-methoxyphenyl)indeno[2,1-a]indene-2-carbonitrile 
• 1095509-63-9 2-phenyl-3-(4-methoxy-benzyl)-2H-indazole 
• 852523-57-0 1-(2-chlorophenyl)-4-methoxybenzene 

Relevant academic research and scientific papers

Atom-Economical Thiocyanation-Amination of Alkynes with N-Thiocyanato-Dibenzenesulfonimide

A highly regioselective protocol for intermolecular thiocyanation-amination of alkynes by N-thiocyano-dibenzenesulfonimide (NTSI) as the SCN and nitrogen sources has been developed. A C-S bond and C-N bond are simultaneously constructed in only one step. The reaction under simple mild conditions features a broad substrate scope, atom economy, high yields (up to 94%), and excellent functional group tolerance.

Gold-Catalyzed Dimerization of Diarylalkynes: Direct Access to Azulenes

We have developed a simple gold-catalyzed procedure for the synthesis of substituted and modifiable azulenes. The azulenes are formed either by the dimerization of push–pull diarylalkynes bearing a fluorine atom in ortho or para position or by the dimeriz

Chemoselective synthesis of unsymmetrical internal alkynes or vinyl sulfones via palladium-catalyzed cross-coupling reaction of sodium sulfinates with alkynes

A highly efficient and mild palladium-catalyzed cross-coupling of sodium sulfinates and alkynes for the selective synthesis of unsymmetrical internal alkynes and vinyl sulfones has been developed. This methodology has advantages of easily accessible starting materials, functional group tolerance and a wide range of substrates, which provides rapid access to alkynes and vinyl sulfones.

High-yielding intramolecular direct arylation reactions with aryl chlorides

(Chemical Equation Presented) An N-heterocyclic carbene palladium catalyst system is used to promote direct arylation of a broad range of aryl chlorides to form six- and five-membered ring biaryls. An influence of the halide on the palladium precatalyst on catalyst activation has been revealed, as has a beneficial effect of NHC salts that allows the turnover numbers to be increased by simple addition of imidazolium salts to the reaction mixture.

Tandem Sonogashira coupling: An efficient tool for the synthesis of diarylalkynes

(Chemical Equation Presented) The tandem Sonogashira coupling reaction of aryl halides provides an efficient method for the synthesis of diarylalkynes. Several aryl halides were coupled with 2-methyl-3-butyn-2-ol as acetylene source in the presence of PdCl2(PPh3)2 and CuI. Following the deprotection of the acetylene moiety in the same pot using a strong base, the Sonogashira coupling of a second aryl halide led to the formation of the appropriate diarylakyne. The established protocoll was successfully extended to the preparation of compound libraries.