478506-32-0 Usage
Uses
Used in Pharmaceutical Industry:
D-[5,5'-2H2]RIBOSE is used as a stable isotope tracer for pharmaceutical research and development. The incorporation of deuterium in the molecule allows for the tracking of metabolic pathways and the study of drug interactions within the body. This is particularly useful in the development of new drugs and the understanding of their mechanisms of action.
Used in Metabolic Research:
In the field of metabolic research, D-[5,5'-2H2]RIBOSE serves as a valuable tool for investigating the role of ribose in various metabolic processes. The stable isotope labeling enables researchers to monitor the fate of ribose in cellular metabolism, providing insights into the regulation of these processes and the potential for therapeutic intervention.
Used in Diagnostic Applications:
D-[5,5'-2H2]RIBOSE can be employed in diagnostic applications, where its stable isotope labeling allows for the detection and quantification of ribose-related metabolites in biological samples. This can be particularly useful in the diagnosis and monitoring of diseases associated with altered ribose metabolism, such as certain genetic disorders or cancer.
Used in Nutritional Studies:
In nutritional research, D-[5,5'-2H2]RIBOSE can be utilized to study the effects of ribose supplementation on energy metabolism and athletic performance. The stable isotope labeling allows for the assessment of ribose absorption, utilization, and excretion, providing valuable information on the optimal dosage and timing of supplementation for various populations.
Check Digit Verification of cas no
The CAS Registry Mumber 478506-32-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,5,0 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 478506-32:
(8*4)+(7*7)+(6*8)+(5*5)+(4*0)+(3*6)+(2*3)+(1*2)=180
180 % 10 = 0
So 478506-32-0 is a valid CAS Registry Number.
478506-32-0Relevant articles and documents
Preparation of specifically deuterated RNA for NMR studies using a combination of chemical and enzymatic synthesis
Tolbert, Thomas J.,Williamson, James R.
, p. 7929 - 7940 (2007/10/03)
The syntheses of ATP, GTP, UTP, and CTP with deuterium labels on the 3', 4', and 5' carbons (2-5) is described. A combination of chemical and enzymatic synthesis is used where D,L-ribose-3,4,5,5'-d4 (±1) is first produced from glycerol-d8
