478511-06-7

Basic information

• Product Name: [3'-13C]THYMIDINE
• Synonyms: [3'-13C]THYMIDINE;Thymidine-3'-13C;QFDWQMZAAKFSTL-PTQBSOBMSA-N
• CAS NO: 478511-06-7
• Molecular Formula: C10H14N2O5
• Molecular Weight: 243.24
• Mol File: 478511-06-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.421 g/cm³
• CAS DataBase Reference: [3'-13C]THYMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: [3'-13C]THYMIDINE(478511-06-7)
• EPA Substance Registry System: [3'-13C]THYMIDINE(478511-06-7)

Safety Data

• Hazardous Substances Data: 478511-06-7(Hazardous Substances Data)

Usage

Description

[3'-13C]THYMIDINE, also known as Thymidine-3'-13C, is a labeled version of Thymidine (T412000), which is a constituent of deoxyribonucleic acid (DNA). The presence of the 13C isotope in the 3' position of the thymidine molecule allows for the tracking and analysis of DNA synthesis and repair processes.

Uses

Used in Molecular Biology and Biochemistry Research:
[3'-13C]THYMIDINE is used as a tracer for studying DNA synthesis and repair mechanisms. The incorporation of the labeled thymidine into newly synthesized DNA strands allows researchers to monitor the process and investigate the underlying molecular pathways.
Used in Medical Diagnostics:
[3'-13C]THYMIDINE is used as a diagnostic tool for detecting and monitoring the proliferation of cells, particularly in the context of cancer. The uptake and incorporation of the labeled thymidine can provide valuable information about the rate of cell division and the effectiveness of cancer treatments.
Used in Pharmaceutical Development:
[3'-13C]THYMIDINE is used as a research compound in the development of new drugs targeting DNA synthesis and repair. By studying the interactions between the labeled thymidine and potential drug candidates, researchers can gain insights into the mechanisms of action and optimize the design of novel therapeutic agents.
Used in Radiocarbon Dating:
Although not explicitly mentioned in the provided materials, [3'-13C]THYMIDINE could potentially be used in radiocarbon dating, particularly in the field of archaeology. The 13C isotope can be used to determine the age of organic materials by measuring the ratio of 13C to 12C isotopes in the sample.