478552-07-7

Upstream product

• 343308-49-6 methyl 4-(3-bromopropoxy)-5-methoxy-2-nitrobenzoate 
• 343308-46-3 methyl 4-(3-bromopropoxy)-3-methoxybenzoate 
• 2133-40-6 L-proline methyl ester monohydrochloride 
• 343308-52-1 4-(3-bromopropoxy)-5-methoxy-2-nitrobenzoic acid 
• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 

Downstream Products

• 478552-12-4 [(S)-2-(Bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-{5-methoxy-4-[3-(4-methyl-piperazin-1-yl)-propoxy]-2-nitro-phenyl}-methanone 
• 478552-18-0 {2-Amino-5-methoxy-4-[3-(4-methyl-piperazin-1-yl)-propoxy]-phenyl}-[(S)-2-(bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-methanone 
• 478552-10-2 [(S)-2-(Bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-[5-methoxy-4-(3-morpholin-4-yl-propoxy)-2-nitro-phenyl]-methanone 
• 478552-11-3 [2-Amino-5-methoxy-4-(3-morpholin-4-yl-propoxy)-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-methanone 
• 478552-15-7 [(S)-2-(Bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-[4-(3-diethylamino-propoxy)-5-methoxy-2-nitro-phenyl]-methanone 
• 478552-19-1 [2-Amino-4-(3-diethylamino-propoxy)-5-methoxy-phenyl]-[(S)-2-(bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-methanone 
• 343308-55-4 (2S)-N-[4-(3-bromopropoxy)-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 478552-08-8 (S)-1-[4-(3-Bromo-propoxy)-5-methoxy-2-nitro-benzoyl]-pyrrolidine-2-carbaldehyde 

Relevant academic research and scientific papers

Synthesis of C-8 alkylamino substituted pyrrolo[2,1-c][1,4]benzodiazepines as potential anti-cancer agents

The design and facile synthesis of C-8 alkylamino substituted pyrrolo[2,1-c][1,4]benzodiazepines is described. These have been prepared by linking the amines at C-8 position with propane spacer to improve solubility in water, and their in vitro cytotoxici