478828-52-3 Usage
Uses
Used in Pharmaceutical Industry:
5-HYDROXYMETHYL-1H-INDAZOLE is used as an intermediate in the preparation of novel Curcumin derivatives, specifically as β-secretase inhibitors. These derivatives have potential applications in the treatment of neurodegenerative diseases, such as Alzheimer's, by targeting the enzymes responsible for amyloid plaque formation in the brain. The hydroxymethyl group in 5-HYDROXYMETHYL-1H-INDAZOLE allows for the attachment of Curcumin molecules, enhancing their inhibitory effects on β-secretase activity.
Check Digit Verification of cas no
The CAS Registry Mumber 478828-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,8,2 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 478828-52:
(8*4)+(7*7)+(6*8)+(5*8)+(4*2)+(3*8)+(2*5)+(1*2)=213
213 % 10 = 3
So 478828-52-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2O/c11-5-6-1-2-8-7(3-6)4-9-10-8/h1-4,11H,5H2,(H,9,10)
