478868-72-3

Upstream product

• 99-91-2 para-chloroacetophenone 
• 5814-38-0 ethyl 4-chlorobenzoylpyruvate 

Downstream Products

• 478868-80-3 5-(4-chloro-phenyl)-1-methyl-4-nitroso-1H-pyrazole-3-carboxylic acid ethyl ester 
• 1221066-54-1 C₁₂H₁₀ClN₃O₃ 
• 478869-20-4 7-chloro-3-(4-chloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-d]pyrimidine 
• 478869-12-4 3-(4-chloro-phenyl)-2,5-dimethyl-2,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one 
• 478868-95-0 4-amino-5-(4-chloro-phenyl)-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents

A novel series of 3,5,6-trisubstituted pyrazolo[4,3-d]pyrimidin-7-one derivatives, especially 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-ones were synthesized and evaluated for their in vitro anticancer activities against various human cancer cell line

3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists.

The synthesis of a series of 3-aryl pyrazolo[4,3-d]pyrimidines as potential corticotropin-releasing factor (CRF-1) antagonists is described. The effects of substitution on the aromatic ring, the amino group and the pyrazolo ring on CRF-1 receptor binding