478962-96-8Relevant academic research and scientific papers
Synthesis of 2-amino-6-(2-[18F]fluoro-pyridine-4-ylmethoxy)-9-(octyl-β- D-glucosyl)-purine: A novel radioligand for positron emission tomography studies of the O6-methylguanine-DNA methyltransferase (MGMT) status of tumour tissue
Schirrmacher, Ralf,Mühlhausen, Ute,W?ngler, Bj?rn,Schirrmacher, Esther,Reinhard, Jost,Nagel, Gerd,Kaina, Bernd,Piel, Markus,Wie?ler, Manfred,R?sch, Frank
, p. 6301 - 6304 (2007/10/03)
The synthesis of the novel glucose conjugated O6-methylguanine-DNA methyltransferase (MGMT) inhibitor 2-amino-6-(2-[18F]fluoro-pyridine-4-ylmethoxy)-9-(octyl- α-D-glucosyl)-purine is reported. This compound might serve as a radiotracer for the determination of the MGMT status of tumour tissue.
