478977-70-7Relevant academic research and scientific papers
Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base
Wang, Ke,Stringfellow, Sandra,Dong, Shiming,Jiao, Yugao,Yu, Hongtao
, p. 2595 - 2603 (2007/10/03)
The fluorescence spectroscopy of 7-azaindole (7aIn) incorporated in DNA oligonucleotides is investigated. Incorporation of 7aIn into DNA oligonucleotides is accomplished through standard solid-phase phosphoramidite chemistry. Fluores
Efforts toward the expansion of the genetic alphabet: Information storage and replication with unnatural hydrophobic base pairs
Ogawa, Anthony K.,Wu, Yiqin,McMinn, Dustin L.,Liu, Jianquan,Schultz, Peter G.,Romesberg, Floyd E.
, p. 3274 - 3287 (2007/10/03)
The faithful recognition of the interstrand hydrogen bonds between complementary nucleobases forms the foundation of the genetic code. The ability to replicate DNA containing a stable third base pair would allow for an expansion of the information content
