4790-38-9

Upstream product

• 1622-32-8 2-Chloroethanesulfonyl chloride 
• 1570-64-5 2-methyl-4-chlorophenol 

Downstream Products

• 20871-70-9 1-Chloro-4-methoxy-5-methyl-2-nitrobenzene 
• 19044-75-8 4-chloro-2-methyl-5-nitro-phenol 
• 923274-95-7 7-Methoxy-6-methyl-2-phenyl-quinazoline-4-ol 
• 923274-94-6 4-Methoxy-5-methyl-2-amino-benzamide 
• 923274-93-5 4-Methoxy-5-methyl-2-nitrobenzamide 
• 923274-92-4 4-methoxy-5-methyl-2-nitro-benzonitrile 
• 923274-91-3 Ethenesulfonic acid 4-chloro-2-methyl-5-nitrophenyl ester 

Relevant academic research and scientific papers

Macrocylic Inhibitors of Hepatitis C Virus

Compounds of the formula I: and N-oxides, salts, and stereoisomers thereof wherein A is OR1, NHS(═O)pR2; wherein; R1 is hydrogen, C1-C6alkyl, C0-C3alkylenecarbocyclyl, C0-C3alkylene-heterocyclyl;R2 is C1-C6alkyl, C0-C3alkylenecarbocyclyl, C0-C3alkyleneheterocyclyl;p is independently 1 or 2;n is 3, 4, 5 or 6; — denotes an optional double bond;L is N or CRz; Rz is H or forms a double bond with the asterisked carbon;Rq is H or when L is CRz, Rq can also be C1-C6alkyl;Rr is quinazolinyl, optionally substituted with one two or three substituents each independently selected from C1-C6 alkyl, C1-C6alkoxy, hydroxyl, halo, haloC1-C6alkyl, amino, mono- or dialkylamino, mono- or dialkylaminocarbonyl, C1-C6alkyl-carbonylamino, C0-C3alkylenecarbocyclyl and C0-C3 alkyleneheterocyclyl;R5 is hydrogen, C1-C6alkyl, C1-C6alkoxyC1-C6alkyl or C3-C7cycloalkyl;R6 is hydrogen, C1-C6alkyl, C1-C6alkoxy, C0-C3alkylenecarbocyclyl, C0-C3alkylene-heterocyclyl, hydroxy, bromo, chloro or fluoro have utility in the treatment or prophylaxis of flaviviral infections such as HCV