479064-40-9

Upstream product

• 479064-37-4 tert-butyl (3R,5S)-3-tert-butyldiphenylsilyloxy-6-hydroxy-8-oxo-1-azaspiro[4.5]decane-1-carboxylate 
• 479064-51-2 tert-butyl (3R,5R)-3-tert-butyldiphenylsilyloxy-6-hydroxy-8-oxo-1-azaspiro[4.5]decane-1-carboxylate 
• 479064-48-7 tert-butyl (2R,4R)-2-(but-3-enyl)-4-tert-butyldiphenylsilyloxy-2-hydroxymethyl-1-pyrrolidinecarboxylate 
• 479064-34-1 tert-butyl (2S,4R)-2-(but-3-enyl)-4-tert-butyldiphenylsilyloxy-2-hydroxymethyl-1-pyrrolidinecarboxylate 
• 479064-50-1 tert-butyl (2R,4R)-4-tert-butyldiphenylsilyloxy-2-formyl-2-(3-oxobutyl)-1-pyrrolidinecarboxylate 
• 479064-36-3 tert-butyl (2S,4R)-4-tert-butyldiphenylsilyloxy-2-formyl-2-(3-oxobutyl)-1-pyrrolidinecarboxylate 
• 479064-49-8 tert-butyl (2R,4R)-2-(but-3-enyl)-4-tert-butyldiphenylsilyloxy-2-formyl-1-pyrrolidinecarboxylate 
• 479064-35-2 tert-butyl (2S,4R)-2-(but-3-enyl)-4-tert-butyldiphenylsilyloxy-2-formyl-1-pyrrolidinecarboxylate 
• 479064-52-3 tert-butyl (3R,5R)-3-tert-butyldiphenylsilyloxy-8-oxo-1-azaspiro[4.5]dec-6-ene-1-carboxylate 
• 479064-38-5 tert-butyl (3R,5S)-3-tert-butyldiphenylsilyloxy-8-oxo-1-azaspiro[4.5]dec-6-ene-1-carboxylate 
• 226225-51-0 2-but-3-enyl-4-(tert-butyl-diphenyl-silanyloxy)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 479064-47-6 2-but-3-enyl-4-(tert-butyl-diphenyl-silanyloxy)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 226225-42-9 (2S,4R)-N-tert-butyloxycarbonyl-4-[(tert-butyldiphenylsilyl)oxy]pyrrolidine-2-carboxylic acid methyl ester 
• 107-21-1 ethylene glycol 

Relevant academic research and scientific papers

Synthesis of (-)-TAN1251A using 4-hydroxy-L-proline as a chiral source

A new synthetic route of (-)-TAN1251A possessing an antimuscarinic activity was developed on the basis of alkylation of a trans-4-hydroxy-L-proline derivative and the subsequent construction of an azaspiro ring as key steps.