479092-60-9

Upstream product

• 1054654-78-2 (12R,13S,14S)-(3E,5E,7E,9E,12E)-16-(tert-butyldiphenylsiloxy)-12-cyano-2-[(E)-ethylidene]-4,10-dimethyl-11-oxo-14-triethylsiloxy-12,13-epoxyhexadeca-3,5,7,9-tetraenoic acid methyl ester 
• 479092-56-3 (14S)-(3E,5E,7E,9E,12E)-16-(tert-butyldiphenylsiloxy)-12-cyano-2-[(E)-ethylidene]-4,10-dimethyl-11-oxo-14-(triethylsiloxy)hexadeca-3,5,7,9,12-pentaenoic acid methyl ester 
• 1053709-51-5 (3E,5E,7E,9E)-11-{(2R,3S)-3-[(S)-3-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-propyl]-2-cyano-oxiranyl}-2-eth-(E)-ylidene-4,10-dimethyl-11-oxo-undeca-3,5,7,9-tetraenoic acid methyl ester 
• 479092-71-2 (S)-4-(tert-butyldiphenylsiloxy)-2-(triethylsiloxy)butyric acid methyl ester 
• 479092-81-4 (S)-4-(tert-butyldiphenylsiloxy)-2-(triethylsiloxy)butan-1-ol 
• 479092-55-2 (S)-4-(tert-butyldiphenylsilyloxy)-2-triethylsiloxybutanal 
• 479092-51-8 (3E,5E,7E,9E)-12-cyano-2-[(E)-ethylidene]-4,10-dimethyl-11-oxododeca-3,5,7,9-tetraenoic acid tert-butyl ester 
• 479092-47-2 (2E,4E,6E,8E)-10-[(E)-ethylidene]-2,8-dimethylundeca-2,4,6,8-tetraenedioic acid 11-tert-butyl ester 1-methyl ester 
• 479092-53-0 (3E,5E,7E,9E)-12-cyano-2-[(E)-ethylidene]-4,10-dimethyl-11-oxododeca-3,5,7,9-tetraenoic acid methyl ester 
• 479092-63-2 (3E,5E,7E,9E)-12-cyano-2-[(E)-ethylidene]-4,10-dimethyl-11-oxododeca-3,5,7,9-tetraenoic acid 
• 479092-37-0 (3E,5E)-tert-butyl [(2E)-ethylidene]-9-hydroxy-4-methyl-nona-3,5-dienate 
• 479092-49-4 (3E,5E,7E)-2-[(E)-ethylidene]-4-methyl-9-oxonona-3,5,7-trienoic acid tert-butyl ester 
• 153011-60-0 Methyl (2S)-4-<(tert-butyldiphenylsilyl)oxy>-2-hydroxybutyrate 
• 479092-58-5 (3E,5E,7E,9E)-11-{(1R,4S,5S)-4-[2-(tert-butyldiphenylsiloxy)ethyl]-2-oxo-3,6-dioxabicyclo[3.1.0]hex-1-yl}-2-[(E)-ethylidene]-4,10-dimethyl-11-oxoundeca-3,5,7,9-tetraenoic acid methyl ester 

Downstream Products

• 479092-75-6 (3E,5E,7E,9E)-11-{(1R,5S)-4-[2-(tert-butyldiphenylsiloxy)ethyl]-4-hydroxy-2-oxo-3-aza-6-oxabicyclo[3.1.0]hex-1-yl}-2-[(E)-ethylidene]-4,10-dimethyl-11-oxoundeca-3,5,7,9-tetraenoic acid methyl ester 

Relevant academic research and scientific papers

The diastereoselective asymmetric total synthesis of NG-391, a neuronal cell-protecting molecule

The stereocontrolled total synthesis of (+)-NG-391, a neuronal cell-protecting molecule, is described along with the determination of its absolute stereochemistry. The following reactions in this synthesis are particularly noteworthy: (1) The stereoselect