479192-15-9

Basic information

• Product Name: Propanal, 3-(4-methoxyphenoxy)-
• CAS NO: 479192-15-9
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol File: 479192-15-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 300.2±22.0 °C(Predicted)
• Density: 1.074±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Propanal, 3-(4-methoxyphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanal, 3-(4-methoxyphenoxy)-(479192-15-9)
• EPA Substance Registry System: Propanal, 3-(4-methoxyphenoxy)-(479192-15-9)

Safety Data

• Hazardous Substances Data: 479192-15-9(Hazardous Substances Data)

Upstream product

• 92971-94-3 β-(4-methoxyphenoxy)propionaldehyde ethylene acetal 
• 150-76-5 4-methoxy-phenol 
• 2653-90-9 1-(but-3-en-1-yloxy)-4-methoxybenzene 
• 13391-35-0 allyl (4-methoxyphenyl) ether 

Downstream Products

• 671798-77-9 (3R,4S)-1-(4-methoxyphenoxy)-4-methylhex-5-en-3-ol 
• 1186430-90-9 (3S,4S,5S)-3-((4-methoxyphenoxy)methyl)-5-nitro-4-phenylcyclohex-1-ene carbaldehyde 
• 1383371-26-3 (6E,17Z,28E)-5,3'-bis((4-methoxybenzyloxy)methyl)-2,4,31,33-tetraoxatetratriaconta-6,17,28-triene 
• 1383371-23-0 (S,E)-14-(4-methoxybenzyloxy)-13-(methoxymethoxy)tetradec-11-en-1-ol 
• 671798-94-0 (2R,3S,5S,6R,8S,9S)-8-[3,5-bis(tert-butyldimethylsilyloxy)phenyl]-2-[2-(4-methoxyphenoxy)ethyl]-3,5,9-trimethyl-1,7-dioxaspiro[5.5]undecane 
• 671798-92-8 (2S,4R,5S)-5-(tert-butyldimethylsilyloxy)-7-(4-methoxyphenoxy)-2,4-dimethylheptanoic acid [(1S,2S)-(2-hydroxy-1-methyl-2-phenylethyl)]methylamide 
• 671798-90-6 (4R,5S)-5-(tert-butyldimethylsilyloxy)-7-(4-methoxyphenoxy)-4-methylheptanoic acid [(1S,2S)-(2-hydroxy-1-methyl-2-phenylethyl)]methylamine 
• 671799-04-5 (4S,5R)-5-(tert-butyldimethylsilyloxy)-7-(4-methoxyphenoxy)-4-methylheptanoic acid pyridin-2-ylmethyl ester 
• 671798-84-8 triethyl{(1R,2S)-1-[2-(4-methoxyphenoxy)ethyl]-2-methylbut-3-enyloxy}silane 
• 671799-02-3 tert-butyl{(1R,2S)-1-[2-(4-methoxyphenoxy)ethyl]-2-methylbut-3-enyloxy}dimethylsilane 
• 671798-86-0 (3S,5S,6R)-6-[2-(4-methoxyphenoxy)ethyl]-3,5-dimethyltetrahydropyran-2-one 

Relevant articles and documents

Biomimetic synthesis and anti-inflammatory evaluation of violacin A analogues

Violacin A, a chromanone derivative, isolated from a fermentation broth of Streptomyces violaceoruber, has excellent anti-inflammatory potential. Herein, a biogenetically modeled approach to synthesize violacin A and twenty-five analogues was described, which involved the preparation of aromatic polyketide precursor through Claisen condensation and its spontaneous cyclization. The inhibitory effect on nitric oxide (NO) production of all synthetic molecules was evaluated by lipopolysaccharide (LPS)-induced Raw264.7 cells. The results revealed that introduction of aliphatic amine moieties on C-7 obviously improved the anti-inflammation effect of violacin A, and also the aromatic ether instead of ketone group at side chain was favorable to increase the activity. Among them, analogue 7a and 16d were screened as the most effective anti-inflammatory candidates. Molecular mechanism research revealed that 7a and 16d acquired anti-inflammatory ability due to the inhibition of NF-κB signaling pathway.

Synthesis of the C16-C35 Fragment of Integramycin Using Olefin Hydroesterification as a Linchpin Reaction

(Matrix presented) The spiroketal unit of the HIV-integrase inhibitor integramycin has been prepared in an efficient and convergent manner. Key steps in this sequence include the use of ruthenium-mediated hydroesterification reactions of homoallylic alcoh