479218-75-2Relevant academic research and scientific papers
Synthesis and thrombolytic activity of pseudopeptides related to fibrinogen fragment
Wu, Yanfen,Zhao, Ming,Wang, Chao,Peng, Shiqi
, p. 2331 - 2333 (2002)
Two kinds of linkers consisting of 3-(S)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, ARPAK, GRPAK and QRPAK were synthesized. The thrombolytic activities in vivo indicated that the coupling position of 3-(S)-1,2,3,4-tetrahydro-β-carboline-3-carboxyl
Carboline-3-carboxylic acid modified related sequences of Ala-Arg-Pro-Ala-Lys, their synthesis and use as thromobolytic agent
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Page/Page column 8-9, (2010/02/11)
The present invention relates to the protected intermediates and the deprotected products of P6A, related to the protected pseudopeptides introducing the protected intermediateds of P6A to 3S-(2-Boc)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid and the deprotected pseudopeptides, related to the protected pseudopeptides introducing the protected intermediateds of P6A to 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid benzyl ester, related to the methods for their preparation, and related to their use as the thrombolytic agents.
