479218-81-0Relevant articles and documents
Carboline-3-carboxylic acid modified related sequences of Ala-Arg-Pro-Ala-Lys, their synthesis and use as thromobolytic agent
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Page/Page column 16, (2010/02/11)
The present invention relates to the protected intermediates and the deprotected products of P6A, related to the protected pseudopeptides introducing the protected intermediateds of P6A to 3S-(2-Boc)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid and the deprotected pseudopeptides, related to the protected pseudopeptides introducing the protected intermediateds of P6A to 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid benzyl ester, related to the methods for their preparation, and related to their use as the thrombolytic agents.
Synthesis and thrombolytic activity of pseudopeptides related to fibrinogen fragment
Wu, Yanfen,Zhao, Ming,Wang, Chao,Peng, Shiqi
, p. 2331 - 2333 (2007/10/03)
Two kinds of linkers consisting of 3-(S)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, ARPAK, GRPAK and QRPAK were synthesized. The thrombolytic activities in vivo indicated that the coupling position of 3-(S)-1,2,3,4-tetrahydro-β-carboline-3-carboxyl