479347-00-7Relevant academic research and scientific papers
Synthesis of 1′-substituted derivatives of 1,2,3,4,5-pentaphenylferrocene
Butler, David C.D.,Richards, Christopher J.
, p. 5433 - 5436 (2008/10/08)
Pentaphenylferrocene was synthesized in 57% overall yield from 1-bromopentaphenylcyclopentadiene. Functionalization of the unsubstituted cyclopentadienyl ring using the Friedel - Crafts reaction gave 1′-formyl-and 1′-(2-chlorobenzoyl)-substituted derivatives. Hydrolysis of the latter provided the corresponding 1′-carboxylic acid. This was readily transformed via a modified Curtius rearrangement into 1′-amino-1,2,3,4,5-pentaphenylferrocene. This methodology also provided (η5-aminocyclopentadienyl)(η4-tetraphenylcyclobuta diene)-cobalt and gave an improved synthesis of aminoferrocene.
