479623-43-3

Basic information

• Product Name: N¹-{2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethyl}-N²-(3,5-dinitrobenzoyl)leucinamide
• Synonyms: N¹-{2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethyl}-N²-(3,5-dinitrobenzoyl)leucinamide
• CAS NO: 479623-43-3
• Molecular Weight: 671.713
• Mol File: 479623-43-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N¹-{2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethyl}-N²-(3,5-dinitrobenzoyl)leucinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-{2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethyl}-N²-(3,5-dinitrobenzoyl)leucinamide(479623-43-3)
• EPA Substance Registry System: N¹-{2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethyl}-N²-(3,5-dinitrobenzoyl)leucinamide(479623-43-3)

Safety Data

• Hazardous Substances Data: 479623-43-3(Hazardous Substances Data)

Upstream product

• 385366-62-1 tert-butyl 2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethylcarbamate 
• 385366-61-0 tert-butyl 2-(4-chloro-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy)ethylcarbamate 
• 7495-01-4 (S)-N-(3,5-dinitrobenzoyl)leucine 
• 385366-63-2 2-[4-(allylamino)-6-{[(1S)-1-(1-naphthyl)ethyl]amino}-1,3,5-triazin-2-yloxy]ethylamine 

Relevant articles and documents

(S)-leucine and [(S)-1-(1-naphthyl)ethyl]amine as chiral building blocks for a bifunctional system - Synthesis of a new chiral stationary phase and evaluation of its biselector properties in the HPLC resolution of racemic compounds

Two selectors derived from [(S)-1-(1-naphthyl)ethyl]amine and (S)-leucine have been chemically bonded to one another and the resulting chiral auxiliary linked covalently to silica gel, to produce a new chiral stationary phase (CSP) for the HPLC resolution of enantiomers. The CSP is able to separate the enantiomers of some selected racemic compounds: both those resolved by Oi's CSP {derived from [1-(1-naphthyl)ethyl]amine} and those enantiodiscriminated by Pirkle's CSP [derived from N-(3,5-dinitrobenzoyl)leucine]. The results obtained demonstrate that the CSP possesses the properties of an efficient biselector system.