479631-37-3

Usage

Uses

Used in Organic Chemistry:
(6-methoxy-naphthalen-2-ylmethyl)-methyl-amine is used as a building block for the synthesis of more complex organic compounds. Its unique structure allows it to be a valuable component in creating a wide range of chemical products.
Used in Pharmaceutical Industry:
(6-methoxy-naphthalen-2-ylmethyl)-methyl-amine is used as a reagent in the development of new drugs or medical treatments. Its potential applications in this industry are diverse and varied, making it a promising candidate for further research and development.
Used in Chemical Reactions:
(6-methoxy-naphthalen-2-ylmethyl)-methyl-amine is used as a reagent in certain chemical reactions, contributing to the formation of desired products or aiding in specific processes within the reaction sequence. Its presence can enhance the efficiency or selectivity of these reactions, making it a useful tool in a chemist's arsenal.

Upstream product

• 60201-22-1 (6-methoxy-2-naphthyl)methanol 
• 3453-33-6 6-methoxynaphthalene-2-carbaldehyde 

Relevant academic research and scientific papers

Gold(i)-catalyzed Nicholas reaction with aromatic molecules utilizing a bifunctional propargyl dicobalt hexacarbonyl complex

A benchtop-stable reagent for the catalytic Nicholas reaction was developed. By combining a propargyl dicobalt hexacarbonyl cluster with an ortho-alkynylbenzoate unit and a fluorous tag, introduction of a propargyl hexacarbonyl complex on various aromatic compounds having acid- or base-sensitive functional groups becomes possible by using a gold(i) catalyst. In addition, the presence of a fluorous tag facilitates convenient separation of the target products from byproducts.

6-(Aryl-amido or aryl-amidomethyl)-naphthalen-2-yloxy-acidic derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)

This invention provides novel compounds, pharmaceutical compositions and methods of treating thrombotic disorders in mammals, the compounds having the formula: Wherein: Ar is phenyl, naphthyl, furanyl, benzofuranyl, indolyl, pyrazolyl, oxazolyl, fluorenyl, phenylcycloalkane where the cycloalkane can be cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl and Ar can be optionally substituted by 1 to 3 groups selected from C1-C6 alkyl, C1-C6 alkoxy, hydroxy, phenyl-(CH2)0-6—, phenyl-(CH2)0-6O—, C3-C6 cycloalkyl, —(CH2)—C3-C6 cycloalkyl, halogen, C1-C3 perflouroalkyl and C1-C3 perfluoroalkoxy where phenyl can be substituted with from 1 to 3 groups selected from C1-C6 alkyl, C1-C6 alkoxy, phenyl, halogen, trifluoromethyl or trifluoromethoxy; R1 is hydrogen, C1-C6 alkyl or phenyl-(CH2)1-6— where phenyl can be substituted with C1-C6 alkyl, C1-C6 alkoxy, halo, trifluoromethyl or trifluoromethoxy; R2 and R3 are H, C1-C6 alkyl, phenyl-(CH2)0-3—, halo and C1-C3 perfluoroalkyl where phenyl can be substituted with C1-C6 alkyl, C1-C6 alkoxy, halo, trifluoromethyl or trifluoromethoxy; R4 is —CHR5CO2H or —CH2-tetrazole where R5 is H or benzyl; and n=0 or 1; or a pharmaceutically acceptable salt or ester form thereof.