4798-87-2

Usage

Uses

Used in Pharmaceutical Industry:
Pyrrolidine, 1-(2,2,4,4-tetramethyl-1,1-dioxido-3-thietanyl)is used as a potential pharmaceutical compound for its unique molecular structure and steric hindrance, which may contribute to the development of new drugs with specific targeting and therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical field, Pyrrolidine, 1-(2,2,4,4-tetramethyl-1,1-dioxido-3-thietanyl)may be utilized as a component in the design of novel pesticides or herbicides, leveraging its structural characteristics to enhance selectivity and effectiveness.
Used in Materials Science:
Pyrrolidine, 1-(2,2,4,4-tetramethyl-1,1-dioxido-3-thietanyl)is used in materials science for its potential to contribute to the development of new materials with unique properties, such as improved stability or specific interactions with other molecules, due to its complex molecular structure and steric hindrance.

Upstream product

• 18143-34-5 methanesulfonyl trimethylsilyl chloride 
• 10147-37-2 Isopropylsulfonyl chloride 

Relevant academic research and scientific papers

Mechanisms of Hydrolysis of (Trimethylsilyl)methanesulfonyl Chloride. Sulfene-Enamine Reactions in Water

Kinetic, product analysis, and deuteration experiments are consistent with the following mechanisms of hydrolysis of (trimethylsilyl)methanesulfonyl chloride (1) (in 0.01 M KCl at 1 deg C): (a) pH /= 10.0, attack of hydroxide anion (i) at silicon to yield sulfene (5) and (ii) at an α-hydrogen to form (trimethylsilyl)sulfene (4), in each case followed by trapping of the sulfene to give either methanesulfonate (3) or (trimethylsilyl)methanesulfonate (6) salts.Aqueous potassium fluoride catalyzes the hydrolysis of 1 with formation of the methanesulfonate 3, evidently by way of silicophilic attack of fluoride anion on 1 with formation of sulfene (5).Reaction of 1 with an enamine 7 in water (at pH 8 or 9), with or without fluoride, gives two characteristic sulfene-enamine products, (i) the four-membered cycloadduct 8 and (ii) the methylsulfonyl aldehyde 9.The same or related products are also obtained from methanesulfonyl, 2-propanesulfonyl, and phenylmethanesulfonyl chlorides and enamines in water (at pH 9).Hydrolysis of 1 is also catalyzed by aniline or triethylamine evidently giving 5.