4803-21-8

Basic information

• Product Name: 4-phenyl-1H-2,1,3-benzothiadiazine 2,2-dioxide
• Synonyms: 4-phenyl-1H-2,1,3-benzothiadiazine 2,2-dioxide
• CAS NO: 4803-21-8
• Molecular Formula: C₁₃H₁₀N₂O₂S
• Molecular Weight: 258.2957
• Mol File: 4803-21-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-phenyl-1H-2,1,3-benzothiadiazine 2,2-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-1H-2,1,3-benzothiadiazine 2,2-dioxide(4803-21-8)
• EPA Substance Registry System: 4-phenyl-1H-2,1,3-benzothiadiazine 2,2-dioxide(4803-21-8)

Safety Data

• Hazardous Substances Data: 4803-21-8(Hazardous Substances Data)

Upstream product

• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 1189-71-5 isocyanate de chlorosulfonyle 

Downstream Products

• 325686-90-6 1-allyl-4-phenyl-1H-2,1,3-benzothiadiazine-2,2-dioxide 
• 4803-25-2 4-phenyl-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide 

Relevant articles and documents

Asymmetric Stepwise Reductive Amination of Sulfonamides, Sulfamates, and a Phosphinamide by Nickel Catalysis

Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in excellent enantiomeric excess. The cyclization of sulfamates and intermolecular reductive amination of a diarylphosphinamide were also successful. Formic acid was used as a safe and economic surrogate of high-pressure hydrogen gas.

Enantioselective synthesis of cyclic sulfamidates via Pd-catalyzed hydrogenation

Using Pd(CF3;CO2)2/(S,S)-f-binaphane as the catalyst, an efficient enantioselective synthesis of cyclic sulfamidates was developed via asymmetric hydrogenation of the corresponding cyclic imines in 2,2,2-trifluoroethanol at room temperature with high enantioselectivities (up to 99% ee).