480424-71-3 Usage
Description
2-TERT-BUTOXYCARBONYLOXYPHENYLBORONIC ACID, PINACOL ESTER is a boronic acid ester that serves as a versatile building block in organic synthesis. It is characterized by the presence of a pinacol ester moiety, which provides stability and protection to the boronic acid functional group, facilitating easier handling and storage. This chemical compound is particularly valuable in the preparation of pharmaceuticals, agrochemicals, and other organic compounds due to its reactivity in cross-coupling reactions for forming carbon-carbon bonds.
Uses
Used in Organic Synthesis:
2-TERT-BUTOXYCARBONYLOXYPHENYLBORONIC ACID, PINACOL ESTER is used as a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its pinacol ester moiety enhances the stability and reactivity of the boronic acid functional group, making it a preferred choice for constructing complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-TERT-BUTOXYCARBONYLOXYPHENYLBORONIC ACID, PINACOL ESTER is used as a key intermediate in the synthesis of drug molecules. Its ability to form carbon-carbon bonds through cross-coupling reactions allows for the creation of diverse and bioactive compounds with potential therapeutic applications.
Used in Agrochemical Industry:
2-TERT-BUTOXYCARBONYLOXYPHENYLBORONIC ACID, PINACOL ESTER is also utilized in the agrochemical industry for the development of new pesticides and other crop protection agents. Its reactivity in organic synthesis enables the production of novel and effective agrochemicals with improved performance and selectivity.
Used in Cross-Coupling Reactions:
As a valuable reagent in organic chemistry, 2-TERT-BUTOXYCARBONYLOXYPHENYLBORONIC ACID, PINACOL ESTER is extensively used in cross-coupling reactions to form carbon-carbon bonds. This application is crucial for the synthesis of complex organic molecules and contributes to the advancement of organic chemistry and its applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 480424-71-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,0,4,2 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 480424-71:
(8*4)+(7*8)+(6*0)+(5*4)+(4*2)+(3*4)+(2*7)+(1*1)=143
143 % 10 = 3
So 480424-71-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H25BO5/c1-15(2,3)21-14(19)20-13-11-9-8-10-12(13)18-22-16(4,5)17(6,7)23-18/h8-11H,1-7H3
480424-71-3Relevant articles and documents
Directed ortho borylation of phenol derivatives catalyzed by a silica-supported iridium complex
Yamazaki, Kenji,Kawamorita, Soichiro,Ohmiya, Hirohisa,Sawamura, Masaya
supporting information; experimental part, p. 3978 - 3981 (2010/10/21)
The directed ortho borylation of phenol derivatives protected with an N,N-diethylcarbamoyl group was efficiently catalyzed by an immobilized monophosphine-Ir system, which was prepared in situ from [Ir(OMe)(cod)] 2 and a silica-supported, compact phosphine. The utility of the carbamoyloxy group as a leaving group for metal-catalyzed cross-coupling reactions was demonstrated by its utilization in the synthesis of a terphenyl derivative.
