480434-52-4

Upstream product

• 3947-62-4 2,3,4,6-tetraacetylglucose 
• 480434-40-0 1-[(benzyloxy)methyl]-3-(1H-indol-3-yl)-4-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-1H-pyrrole-2,5-dione 
• 480434-39-7 1-[(benzyloxy)methyl]-3-bromo-4-[1-(phenylsulphonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-1H-pyrrole-2,5-dione 
• 480434-38-6 1-[(benzyloxy)methyl]-3-bromo-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1H-pyrrole-2,5-dione 
• 120-72-9 indole 
• 102147-52-4 N-benzyloxymethyl-3,4-dibromomaleimide 
• 271-63-6 7-Azaindole 

Relevant academic research and scientific papers

Pyrido-pyrido-pyrrolo pyrrolo-indole and pyrido-pyrrolo pyrrolo carbazole derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives

Compounds of formula (I): wherein: W1 and W2, together with the carbon atoms to which they are bonded, represent a phenyl group or a pyridyl group, and at least one of the groups W1 or W2 represents a pyridyl group, R1 and R2 each represent a group of formula U-V as defined in the description, X and X1 each represent a hydrogen atom or a hydroxy, alkoxy, mercapto or alkylthio group, Y and Y1 each represent a hydrogen atom, or X and Y, X1 and Y1, together with the carbon atom carrying them, represent a carbonyl or thiocarbonyl group, R4 and R5 are as defined in the description, Q1, Q2 represent a hydrogen atom, or Q1 and Q2, together with the carbon atoms carrying them, form an aromatic bond. Medicaments.

Syntheses and antiproliferative activities of 7-azarebeccamycin analogues bearing one 7-azaindole moiety

Rebeccamycin analogues containing one azaindole unit, with and without a methyl group on the imide nitrogen and with the sugar moiety coupled either to the indole nitrogen or to the azaindole nitrogen were synthesized. To increase the solubility and induc