480439-13-2

Upstream product

• 154364-61-1 ethyl 6-ethoxy-2-hydroxybenzoate 

Downstream Products

• 1383934-16-4 N-[4-chloro-3-(trifluoromethyl)benzyl]-2-ethoxy-6-hydroxybenzamide 
• 1311423-91-2 N-(4-chloro-3-(trifluoromethyl)phenyl)-2-ethoxy-6-hydroxybenzamide 
• 1383934-18-6 N-[4-chloro-3-(trifluoromethyl) phenyl]-2-ethoxy-6-[2-(piperidin-1-yl)ethoxy]benzamide 
• 1383934-19-7 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-(2-morpholinoethoxy)benzamide 
• 1383934-17-5 N-[4-chloro-3-(trifluoromethyl)benzyl]-2-(2-(dimethylamino)ethoxy)-6-ethoxybenzamide 
• 1383934-24-4 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-[2-(piperazin-1-yl)ethoxy]benzamide 
• 1383934-25-5 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-[2-(4-methylpiperazin-1-yl)ethoxy]benzamide 
• 1383934-26-6 N-(4-chloro-3-(trifluoromethyl)phenyl)-2-(2-(diethylamino)ethoxy)-6-ethoxybenzamide 
• 1383934-27-7 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[3-(dimethylamino)propoxy]-6-ethoxybenzamide 
• 1383934-28-8 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[3-(diethylamino)propoxy]-6-ethoxybenzamide 
• 1383934-33-5 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-(isopentyloxy)benzamide 
• 1311423-89-8 YF₂ 
• 1312005-62-1 C₂₀H₂₂ClF₃N₂O₃*ClH 
• 1383934-30-2 2-[((4-chloro-3-(trifluoromethyl)phenyl)amino)methyl]-3-ethoxyphenol 

Relevant academic research and scientific papers

HISTONE ACETYLTRANSFERASE ACTIVATORS AND COMPOSITIONS AND USES THEREOF

The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.

HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

USES OF HISTONE ACETYLTRANSFERASE ACTIVATORS

The invention provides methods for enhancing histone acylation, learning, memory and/or cognition in subjects with compound (I) or compositions comprising compound (I), or a pharmaceutically acceptable salt thereof.

HISTONE ACETYLTRANSFERASE MODULATORS AND USESE THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.