480463-71-6Relevant academic research and scientific papers
5-Fluoro-2-methyl-N-[5-(5H-pyrrolo[2,1-c][1,4]benzodiazepine-10(11H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists
Aranapakam, Venkatesan,Albright, J. Donald,Grosu, George T.,Delos Santos, Efren G.,Chan, Peter S.,Coupet, Joseph,Ru, Xun,Saunders, Trina,Mazandarani
, p. 1737 - 1740 (2007/10/03)
Synthesis and structure-activity relationships (SAR) of orally active arginine vasopressin (AVP) receptor antagonists are discussed. Potent and orally active AVP receptor antagonists are produced when ring A of VPA-985 (1) is replaced with a 3-pyridinyl unit (2b).
