480997-20-4

Basic information

• Product Name: (3aR,6S,6aS)-6-Benzyl-octahydro-cyclopenta[b]pyrrol-6-ol
• CAS NO: 480997-20-4
• Molecular Weight: 217.311
• Mol File: 480997-20-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3aR,6S,6aS)-6-Benzyl-octahydro-cyclopenta[b]pyrrol-6-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,6S,6aS)-6-Benzyl-octahydro-cyclopenta[b]pyrrol-6-ol(480997-20-4)
• EPA Substance Registry System: (3aR,6S,6aS)-6-Benzyl-octahydro-cyclopenta[b]pyrrol-6-ol(480997-20-4)

Safety Data

• Hazardous Substances Data: 480997-20-4(Hazardous Substances Data)

Downstream Products

• 480997-24-8 ((3aR,6S,6aS)-6-Benzyl-6-hydroxy-hexahydro-cyclopenta[b]pyrrol-1-yl)-pyridin-3-yl-methanone 

Relevant articles and documents

Stereoselective synthesis of 1,2- and 1,4-dihydropyridines by using cation-π interaction as a conformation-controlling tool

Selective shielding of one side of the pyridinium face by way of intramolecular cation-π complex formation enabled nucleophiles to attack the pyridinium ring from the non-shielded side. As a result, 1,2- and 1,4-dihydropyridines were formed in good stereoselectivities. 1H NMR analysis and ab initio calculations at the RHF/3-21G* level supported the existence of cation-π interaction between the pyridinium and the aromatic ring of the chiral auxiliary.