481-16-3 Usage
Description
(3beta,22E,24R)-stigmasta-5,22-dien-3-ol is a steroidal compound derived from various plant species, particularly found in seeds and oils. It is distinguished by its 5,22-diene structure and a hydroxyl group at the third position. (3beta,22E,24R)-stigmasta-5,22-dien-3-ol exhibits multiple biological activities, such as anti-inflammatory, antioxidant, and anticancer properties, making it a subject of interest for pharmaceutical development. Furthermore, it has been studied for its role in plant growth and development, as well as its contribution to the nutritional and health benefits of certain plant-derived products.
Uses
Used in Pharmaceutical Industry:
(3beta,22E,24R)-stigmasta-5,22-dien-3-ol is used as a pharmaceutical compound for its diverse biological activities. (3beta,22E,24R)-stigmasta-5,22-dien-3-ol's anti-inflammatory and antioxidant properties make it a potential candidate for the development of drugs targeting inflammation and oxidative stress-related conditions. Additionally, its anticancer properties are being investigated for the creation of novel therapeutic agents against various types of cancer.
Used in Plant Science Research:
In the field of plant science, (3beta,22E,24R)-stigmasta-5,22-dien-3-ol is used as a subject of study to understand its role in plant growth and development. Research in this area may lead to advancements in plant breeding and cultivation techniques, ultimately enhancing crop yields and quality.
Used in Nutritional and Health Products:
(3beta,22E,24R)-stigmasta-5,22-dien-3-ol is also used in the development of nutritional and health products due to its presence in plant-derived products and its associated health benefits. (3beta,22E,24R)-stigmasta-5,22-dien-3-ol's antioxidant and anti-inflammatory properties may contribute to the development of supplements and functional foods that promote overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 481-16-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 481-16:
(5*4)+(4*8)+(3*1)+(2*1)+(1*6)=63
63 % 10 = 3
So 481-16-3 is a valid CAS Registry Number.
481-16-3Relevant articles and documents
NOVEL METHOD FOR SYNTHESIZING 25-OH CHOLESTEROL/CALCIFEDIOL FROM PHYTOSTEROL
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Page/Page column 18-19, (2020/11/23)
The present invention discloses novel method for synthesizing vegan 25-OH cholesterol/Calcifediol from inexpensive crude phytosterol. According to the method, Phytosterols are reacted to form corresponding i-steroid through tosylation and methanolysis. i-steroid on reductive ozonolysis to C-22 alcohol and conversion via C-22 tosylate to C-22 iodide in good yield. Coupling of C-22 tosylate with Grignard reagent of 4-bromo-2-methyl-2-[(trimethylsilyl)oxy] butane followed by deprotection yielded 25-OH cholesterol. In a process variant, nickel mediated conjugate addition of C-22 iodide to an electron deficient alkene ethyl acrylate and treating corresponding ester with methyl magnesium bromide as means of installing the side chain of 25-OH cholesterol in high yield. Further bromination reaction of 25-OH cholesterol diacetate followed by dehydrobromination using TBAF yielded 25-OH 7-dehydrocholesterol. Further photo reaction of 25-OH 7-dehydrocholesterol in to previtamin D3 using high or medium pressure mercury lamp and subsequent thermal reaction of previtamin D3 to 25-OH vitamin D3(Calcifediol) in good yield.
Process for recovery of plant sterols from by-product of vegetable oil refining
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Page/Page column 5-6, (2008/06/13)
The process for recovery of plant sterols and tocopherols from deodorization distillates formed during chemical or physical refining of vegetable oils consists of the following steps: free fatty acids are removed from the deodorization distillate by vacuum distillation or by continuation solvent saponification, after the removal of free fatty acids, the received material is reacted with an aromatic carboxylic acid anhydride at a temperature of 50-150° C., under reduced pressure, after the treatment with anhydride, tocopherols are removed from the mixture, and crystalline free sterols are recovered from the distillation residue containing sterol esters, di- and triglycerides by transesterification.
