481038-65-7Relevant articles and documents
Substituted piperazines as novel dipeptidyl peptidase IV inhibitors
Brockunier, Linda L.,He, Jiafang,Colwell Jr., Lawrence F.,Habulihaz, Bahanu,He, Huaibing,Leiting, Barbara,Lyons, Kathryn A.,Marsilio, Frank,Patel, Reshma A.,Teffera, Yohannes,Wu, Joseph K.,Thornberry, Nancy A.,Weber, Ann E.,Parmee, Emma R.
, p. 4763 - 4766 (2007/10/03)
The synthesis and SAR of a series of piperazines containing a fluorophenyl β-amino amide moiety is reported. Incorporation of a fluorophenyl β-amino amide moiety into piperazine screening lead 2 has resulted in the discovery of a structurally novel series