481049-41-6Relevant academic research and scientific papers
Imidazo[1,2-a]pyridines with potent activity against herpesviruses
Gudmundsson, Kristjan S.,Johns, Brian A.
, p. 2735 - 2739 (2008/02/02)
Synthesis of a series of 2-aryl-3-pyrimidyl-imidazo[1,2-a]pyridines with potent activity against herpes simplex viruses is described. Synthetic approaches allowing for variation of the 2-aryl, 3-heteroaryl as well as other imidazopyridine substituents are
Imidazopyridazines. XVIII. Syntheses and Central Nervous System Activities of Some 6-, 7- and 8-(Chloro and methoxy)imidazopyridine Analogues
Barlin, Gordon B.,Davies, Les P.,Harrison, Peter W.
, p. 1031 - 1038 (2007/10/02)
Syntheses are reported for some 2-aryl-3-(benzamidomethyl and methoxy)-6(7 and 8)-chloro- and 6(and 8)-methoxy-imidazopyridines.In tests of the ability of these compounds to displace diazepam from rat brain membrane, those with 6-chloro and 6-methoxy groups bound most strongly, and relatively small differences only were observed between corresponding imidazopyridines and imidazopyridazines.
