481659-95-4Relevant academic research and scientific papers
In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity
Li, Jin,Bronk, Brian S.,Dirlam, John P.,Blize, Alan E.,Bertinato, Peter,Jaynes, Burton H.,Hickman, Anne,Miskell, Christine,Pillai, Usha A.,Tibbitts, Jay S.,Haven, Michelle L.,Kolosko, Nicole L.,Barry, Chris J.,Manion, Tara B.
, p. 1996 - 1999 (2007)
The synthesis of a novel gut selective MTP inhibitor, 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), and its in vitro and in vivo profile are described. Dirlotapide (3) demonstrate
