4817-67-8

Upstream product

• 349-00-8 N-trifluoroacetyl-L-valine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 72-18-4 L-valine 
• 2357-39-3 2-trifluoromethyl-4-isopropyl-Δ³-oxazolin-5-one 
• 78395-22-9 methyl ester of N-trifluoroacetyldehydrovalylphenylalanine 
• 110582-75-7 2-trifluoromethyl-4-isopropylidene-Δ²-oxazolin-5-one 

Relevant academic research and scientific papers

The: Ortho -substituent on 2,4-bis(trifluoromethyl)phenylboronic acid catalyzed dehydrative condensation between carboxylic acids and amines

2,4-Bis(trifluoromethyl)phenylboronic acid is a highly effective catalyst for dehydrative amidation between carboxylic acids and amines. Mechanistic studies suggest that a 2:2 mixed anhydride is expected to be the only active species, and the ortho-substituent of boronic acid plays a key role in preventing the coordination of amines to the boron atom of the active species, thus accelerating the amidation. This catalyst works for α-dipeptide synthesis.

Chiral Environments for Asymmetric Hydrogenation of Model Didehydro-Amino Acid Residues

Nmr and glc analysis of diastereoisomeric mixtures of dipeptides has been used to study the asymmetric hydrogenation of model benzoyldidehydro- and trifluoroacetyldidehydro-dipeptide methyl esters.Chiral enhancement of one isomeric form appears to be inde