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1-(Trimethylsilyl)-1H-Benzotriazole, commonly referred to as TBTU, is a versatile chemical compound that serves as a coupling reagent in the synthesis of peptides. It is characterized by its white to off-white powder form and its solubility in various common organic solvents. TBTU is recognized for its high efficiency in activating carboxylic acids, which facilitates the formation of peptide bonds with notably low racemization rates. This makes it a preferred choice in solid-phase peptide synthesis and other organic synthesis reactions, particularly within the pharmaceutical and biotechnology sectors for the development of novel peptide-based drugs and bioactive compounds.

48183-36-4

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48183-36-4 Usage

Uses

Used in Pharmaceutical and Biotechnology Industries:
1-(Trimethylsilyl)-1H-Benzotriazole is used as a coupling reagent for the synthesis of new peptide-based drugs and bioactive compounds due to its high efficiency in activating carboxylic acids and promoting peptide bond formation with low racemization rates.
Used in Solid-Phase Peptide Synthesis:
1-(Trimethylsilyl)-1H-Benzotriazole is used as a key component in solid-phase peptide synthesis, where it aids in the efficient formation of peptide bonds, contributing to the development of complex peptide structures with minimal side reactions.
Used in Organic Synthesis Reactions:
Beyond peptide synthesis, 1-(Trimethylsilyl)-1H-Benzotriazole is utilized in various organic synthesis reactions as a coupling reagent, enhancing the efficiency of chemical processes and the yield of desired products.

Check Digit Verification of cas no

The CAS Registry Mumber 48183-36-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,8,1,8 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 48183-36:
(7*4)+(6*8)+(5*1)+(4*8)+(3*3)+(2*3)+(1*6)=134
134 % 10 = 4
So 48183-36-4 is a valid CAS Registry Number.

48183-36-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(TRIMETHYLSILYL)-1H-BENZOTRIAZOLE

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:48183-36-4 SDS

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