4819-36-7

Basic information

• Product Name: (S)-2-AMINO-3-(1,2,4-TRIAZOL-1-YL)PROPIONIC ACID
• Synonyms: (S)-2-AMINO-3-(1,2,4-TRIAZOL-1-YL)PROPIONIC ACID;3-(1,2,4-TRIAZOL-1-YL)-L-ALANINE;(aS)-a-Amino-1H-1,2,4-triazole-1-propanoic Acid
• CAS NO: 4819-36-7
• Molecular Formula: C5H8N4O2
• Molecular Weight: 156.14
• Product Categories: Amino Acids & Derivatives;Metabolites & Impurities
• Mol File: 4819-36-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 402.9°C at 760 mmHg
• Flash Point: 197.5°C
• Appearance: /
• Density: 1.62g/cm³
• Vapor Pressure: 3.24E-07mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-2-AMINO-3-(1,2,4-TRIAZOL-1-YL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-AMINO-3-(1,2,4-TRIAZOL-1-YL)PROPIONIC ACID(4819-36-7)
• EPA Substance Registry System: (S)-2-AMINO-3-(1,2,4-TRIAZOL-1-YL)PROPIONIC ACID(4819-36-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36/37
• WGK Germany: 3
• Hazardous Substances Data: 4819-36-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 4819-36-7 differently. You can refer to the following data:
1. A metabolite common to all triazole fungicides: free triazole, 1,2,4-triazole (T), and its 2 conjugates: triazolylalanine (TA) and triazolylacetic acid (TAA)
2. A metabolite common to all triazole fungicides: free triazole, 1,2,4-triazole (T), and its 2 conjugates: triazolylalanine (TA) and triazolylacetic acid (TAA).

InChI:InChI=1/C5H8N4O2/c6-4(5(10)11)1-9-3-7-2-8-9/h2-4H,1,6H2,(H,10,11)/t4-/m0/s1

Upstream product

• 288-88-0 1,2,4-Triazole 
• 407-41-0 L-phosphoserine 
• 5147-00-2 O-acetyl-L-serine 

Relevant articles and documents

Unnatural amino acid synthesis by thermostable O-phospho-L-serine sulfhydrylase from hyperthermophilic archaeon Aeropyrum pernix K1

O-Acetyl-L-serine sulfhydrylase (OASS) from plants and bacteria synthesizes cysteine and unnatural amino acids that are important building blocks for active pharmaceuticals and agrochemicals. A thermostable O-phospho-L-serine sulfhydrylase from hyperthermophilic archaeon Aeropyrum pernix K1 (OPSSAp) exhibits a function similar to OASS. In the present study, we examined the synthesis of various unnatural amino acids using OPSSAp and demonstrated OPSSAp could efficiently synthesize various sulfur-containing amino acids. OPSSAp would be useful for industrial production of biologically important unnatural amino acids.

BIOSYNTHESIS OF β-(1,2,4-TRIAZOL-1-YL)ALANINE IN HIGHER PLANTS

β-(1,2,4-triazol-1-yl)Alanine, an important metabolite of the triazole-based fungicide Myclobutanil, was shown to be derived from O-acetyl-L-serine and 1,2,4-triazole by cysteine synthase in higher plants.Some properties of this enzyme in the biosynthesis of β-(1,2,4-triazol-1-yl)alanine are described.