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Cinchonamine is an alkaloid compound derived from the bark of certain species of trees in the genus Cinchona. It is structurally related to quinine, a renowned antimalarial drug also sourced from Cinchona bark. Cinchonamine has been the subject of research for its potential pharmacological properties, which include anti-inflammatory, antioxidant, and anti-cancer activities. Additionally, it has demonstrated antimicrobial effects against specific bacteria and fungi. Its unique chemical structure has also made it a candidate for the synthesis of other pharmaceutical compounds, indicating its potential therapeutic applications in medicine and drug development.

482-28-0

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482-28-0 Usage

Uses

Used in Pharmaceutical Industry:
Cinchonamine is used as a precursor in the synthesis of pharmaceutical compounds due to its unique chemical structure, which allows for the development of new drugs with potential therapeutic benefits.
Used in Antimicrobial Applications:
Cinchonamine is utilized as an antimicrobial agent for its effects against certain bacteria and fungi, providing an alternative for treating infections caused by these microorganisms.
Used in Anticancer Research:
Cinchonamine is employed as a subject of research for its potential anti-cancer properties, with the aim of identifying its role in inhibiting tumor growth and progression.
Used in Anti-inflammatory and Antioxidant Therapies:
Cinchonamine is explored for its potential use in anti-inflammatory and antioxidant therapies, given its demonstrated activities that could contribute to the treatment of conditions associated with inflammation and oxidative stress.

Check Digit Verification of cas no

The CAS Registry Mumber 482-28-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 482-28:
(5*4)+(4*8)+(3*2)+(2*2)+(1*8)=70
70 % 10 = 0
So 482-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H24N2O/c1-2-13-12-21-9-7-14(13)11-18(21)19-16(8-10-22)15-5-3-4-6-17(15)20-19/h2-6,13-14,18,20,22H,1,7-12H2/t13-,14-,18-/m0/s1

482-28-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-[(2S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-1H-indol-3-yl]ethanol

1.2 Other means of identification

Product number -
Other names Cinchonamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:482-28-0 SDS

482-28-0Relevant academic research and scientific papers

ORGANOMETALLIC REAGENTS IN SYNTHESIS A NEW PROTOCOL FOR CONSTRUCTION OF THE INDOLE NUCLEUS

Smith, III, Amos B.,Visnick, Melean,Haseltine, John N.,Sprengeler, Paul A.

, p. 2957 - 2970 (2007/10/02)

Organodilithium reagents derived from 2-alkyl-N-trimethylsilyl anilines undergo condensation with esters of carboxylic acids to afford substituted indoles.A total of 16 examples are reported; yields in general were good.In conjuction with this program, a convenient, large-scale procedure for preparation of monosilylated anilines was also developed.To demonstrate the utility of the new indole protocol in natural products synthesis, efficient syntheses of (+)-cinchonamine and (+)-epi-cinchonamine as well as a tetracyclic model system for the architecturally complex penitrem mycotoxins were completed in regio- and stereoselective fashion.

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