482281-07-2

Basic information

• Product Name: N-phenylacetyl-4-chloro-L-phenylalanine
• Synonyms: N-phenylacetyl-4-chloro-L-phenylalanine
• CAS NO: 482281-07-2
• Molecular Weight: 317.772
• Mol File: 482281-07-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenylacetyl-4-chloro-L-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenylacetyl-4-chloro-L-phenylalanine(482281-07-2)
• EPA Substance Registry System: N-phenylacetyl-4-chloro-L-phenylalanine(482281-07-2)

Safety Data

• Hazardous Substances Data: 482281-07-2(Hazardous Substances Data)

Upstream product

• 7424-00-2 DL-Phe(4Cl) 
• 103-81-1 Benzeneacetamide 

Relevant articles and documents

Alcaligenes faecalis penicillin G acylase-catalyzed enantioselective acylation of dl-phenylalanine and derivatives in aqueous medium

A new strategy based on enantioselective acylation properties of relatively unknown penicillin G acylase from Alcaligenes faecalis has been developed for the production of pharmacologically interesting enantiomerically pure d-phenylalanine. In order to get high reaction rate and enantioselectivity, two key factors (pH and temperature) and eight different acyl donors were optimized, and the optimal acylation reaction was carried out at pH 10, 35 °C, using phenylacetamide as the acyl donor. This enantioselective acylating method is also illustrated by the effective production of five different p-substituted phenylalanine derivatives in enantiopure.