482308-13-4

Usage

Uses

Used in Pharmaceutical Industry:
4-(2,4-diaminophenyl)morpholin-3-one is used as a key intermediate in the synthesis of BAY 59-7939, an antithrombotic agent. 4-(2,4-diaminophenyl)morpholin-3-one is particularly important for the development of new treatments for conditions related to blood clotting, such as deep vein thrombosis and pulmonary embolism.
Application Reason:
The use of 4-(2,4-diaminophenyl)morpholin-3-one in the synthesis of BAY 59-7939 is due to its ability to provide a structural framework that can be further modified to create a potent antithrombotic agent. The presence of the morpholine ring and the phenyl group with two amino substituents allows for the formation of various chemical bonds and interactions, which are crucial for the biological activity of the final product.

Relevant academic research and scientific papers

COMBINATION THERAPY OF SUBSTITUTED OXAZOLIDINONES

The present invention relates to combinations of A) oxazolidinones of the formula (I) with B) acetylsalicylic acid (aspirin) and C) an ADP receptor antagonist, in particular P2Y12 purinoreceptor blocker, to a process for producing these combinations and to the use thereof as medicaments, in particular for the prophylaxis and/or treatment of thromboembolic disorders.

MICROANGIOPATHY TREATMENT AND PREVENTION

The present invention relates to the use of selective factor Xa inhibitors, in particular of oxazolidinones of the formula (I) for the treatment and/or prophylaxis of microangiopathies and also their use for the production of medicaments for the treatment and/or prophylaxis of microangiopathies.

Combination Therapy Comprising Substituted Oxazolidinones for the Prevention and Treatment of Cerebral Circulatory Disorders

The present invention relates to combinations of A) oxazolidinones of the formula (I), with B) antiarrhythmics, processes for the production of these combinations, their use for the prophylaxis and/or treatment of diseases, and their use for the manufacture of medicaments for the prophylaxis and/or treatment of diseases, especially of thromboembolic disorders and/or complications.

Substituted oxazolidinones and their in the field of blood coagulation

The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.