482374-29-8Relevant articles and documents
Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres
Oishi, Shinya,Niida, Ayumu,Kamano, Takae,Miwa, Yoshihisa,Taga, Tooru,Odagaki, Yoshihiko,Hamanaka, Nobuyuki,Yamamoto, Mikio,Ajito, Keiichi,Tamamura, Hirokazu,Otaka, Akira,Fujii, Nobutaka
, p. 1786 - 1793 (2002)
Organocopper-mediated alkylation of β-(N-Boc-2-oxo-1,3-oxazolidin-5-yl)-α,β-enoates has been intensively investigated. Alkylation proceeded regio- and stereoselectively by anti-SN2′ ring-opening to provide a new route to the synthesis of Ψ[(E)-