4825-75-6 Usage
Uses
Used in Organic Synthesis:
3-METHYL-1,2-BENZISOXAZOLE is used as a synthetic building block for the development of various organic compounds. Its unique structure and properties make it a versatile component in the synthesis of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-METHYL-1,2-BENZISOXAZOLE is utilized as a key intermediate in the synthesis of novel drug candidates. Its incorporation into drug molecules can potentially enhance their pharmacological properties, such as potency, selectivity, and bioavailability, leading to the development of more effective therapeutic agents.
Used in Agrochemical Industry:
3-METHYL-1,2-BENZISOXAZOLE also finds application in the agrochemical industry, where it is employed in the synthesis of new pesticides and other crop protection agents. Its unique chemical properties can contribute to the development of innovative products with improved performance and selectivity, ultimately benefiting agricultural productivity and sustainability.
Used in Specialty Chemicals:
In the specialty chemicals sector, 3-METHYL-1,2-BENZISOXAZOLE is used as a starting material for the production of various high-value chemicals. These can include dyes, pigments, and other functional materials with specific applications in industries such as textiles, plastics, and coatings. Its versatility and reactivity make it an attractive choice for the development of new and improved specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 4825-75-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,2 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4825-75:
(6*4)+(5*8)+(4*2)+(3*5)+(2*7)+(1*5)=106
106 % 10 = 6
So 4825-75-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO/c1-6-7-4-2-3-5-8(7)10-9-6/h2-5H,1H3
4825-75-6Relevant academic research and scientific papers
A divergent and selective synthesis of isomeric benzoxazoles from a single N-Cl imine
Chen, Cheng-Yi,Andreani, Teresa,Li, Hongmei
, p. 6300 - 6303 (2012/01/05)
A divergent and regioselective synthesis of either 3-substituted benzisoxazoles or 2-substituted benzoxazoles from readily accessible ortho-hydroxyaryl N-H ketimines is described. The reaction proceeds in two distinct pathways through a common N-Cl imine intermediate: (a) N-O bond formation to form benzisoxazole under anhydrous conditions and (b) NaOCl mediated Beckmann-type rearrangement to form benzoxazole, respectively. The reaction path also depends on the electronic nature of the aromatic ring, with the electron-rich aromatic rings favoring the rearrangement and the electron-deficient rings favoring the N-O bond formation. A Beckmann-type rearrangement mechanism via net [1,2]-aryl migration for the formation of 2-substituted benzoxazole is proposed.
Reactivity of 1,2-Benzisoxazole 2-Oxides
Boulton, A. J.,Tsoungas, Petros G.,Tsiamis, Chris
, p. 695 - 698 (2007/10/02)
Nitration, bromination, and reaction with acetic anhydride, with halogen acids, and with sodium alkoxide, have been explored in the 1,2-benzisoxazole 2-oxide series.The nitration proceeded by simple substitution; the other reactions took place with rupture of the heterocyclic ring.Deoxygenation to the 1,2-benzisoxazoles could be accomplished, under forcing conditions.
