482631-88-9

Upstream product

• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 63029-05-0 methyl 5-deoxy-5-iodo-β-D-ribofuranoside 
• 70831-62-8 methyl 2,3-di-O-benzyl-β-D-ribofuranoside 
• 7473-45-2 1-O-methyl-D-ribofuranose 
• 1251531-61-9 Methyl 2,3 di-O-benzyl-5-O-trityl-D-ribofuranoside 

Downstream Products

• 916599-94-5 (1R,2R,3R,4R,5R,6S,8R)-4,5-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-dimethyl-silanyloxymethyl)-2-methyl-11-methylene-12-oxa-tricyclo[6.3.1.0^1,6]dodecane 
• 916599-85-4 acetic acid 6-[3,4-bis-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-hex-5-enyl]-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-5,6-dihydro-2H-pyran-2-yl ester 
• 916599-87-6 (1S,2R,3R,4R,5R,6R,8R)-4,5-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-dimethyl-silanyloxymethyl)-2-methyl-12-oxa-tricyclo[6.3.1.0^1,6]dodec-9-en-11-one 
• 916599-86-5 (1R,2R,3R,4R,5R,6S,8S)-4,5-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-dimethyl-silanyloxymethyl)-2-methyl-12-oxa-tricyclo[6.3.1.0^1,6]dodec-9-en-11-one 
• 916599-84-3 (1S,2S,3R,4R,5R)-4,5-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-[5-(tert-butyl-dimethyl-silanyloxymethyl)-furan-2-yl]-2-methyl-hept-6-en-1-ol 
• 916600-02-7 Acetic acid (1R,2R,3R)-2,3-bis-benzyloxy-1-{(1R,2S)-2-[5-(tert-butyl-dimethyl-silanyloxymethyl)-furan-2-yl]-1-methyl-2-trimethylsilanyloxy-ethyl}-pent-4-enyl ester 
• 916600-05-0 Acetic acid (S)-6-((1R,2R,3R,4R)-2-acetoxy-3,4-bis-benzyloxy-1-methyl-hex-5-enyl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-5,6-dihydro-2H-pyran-2-yl ester 
• 916600-01-6 (1S,2R,3R,4S,5R)-4,5-Bis-benzyloxy-1-[5-(tert-butyl-dimethyl-silanyloxymethyl)-furan-2-yl]-2-methyl-1-trimethylsilanyloxy-hept-6-en-3-ol 
• 916600-04-9 Acetic acid (1R,2R,3R)-2,3-bis-benzyloxy-1-{(R)-1-[(S)-6-(tert-butyl-dimethyl-silanyloxymethyl)-6-hydroxy-3-oxo-3,6-dihydro-2H-pyran-2-yl]-ethyl}-pent-4-enyl ester 
• 916600-03-8 Acetic acid (1R,2R,3R)-2,3-bis-benzyloxy-1-{(1S,2S)-2-[5-(tert-butyl-dimethyl-silanyloxymethyl)-furan-2-yl]-2-hydroxy-1-methyl-ethyl}-pent-4-enyl ester 
• 916599-83-2 (1S,2R,3R,4S,5R)-4,5-Bis-benzyloxy-1-[5-(tert-butyl-dimethyl-silanyloxymethyl)-furan-2-yl]-2-methyl-hept-6-ene-1,3-diol 
• 916599-82-1 (4R,5R)-4,5-Bis-benzyloxy-hept-6-en-3-one 
• 916599-91-2 (4S,5R)-4,5-Bis-benzyloxy-hept-6-en-3-ol 

Relevant academic research and scientific papers

Studies on oxidopyrylium [5 + 2] cycloadditions: Toward a general synthetic route to the C12-hydroxy daphnetoxins

12-Hydroxydaphnetoxins, members of the structurally fascinating daphnane diterpene family, exhibit a wide range of significant biological activities. A general route to the BC-ring system of 12-hydroxy daphnetoxins is reported based on D-ribose. Depending on the choice of protecting groups and solvent, the oxidopyrylium-alkene [5 + 2] cycloaddition originating from A provides cycloadduct diastereomer B or C with good to excellent selectivity.

Regioselective conversion of primary alcohols into iodides in unprotected methyl furanosides and pyranosides

Two methods are described for the regioselective displacement of the primary hydroxy group in methyl glycosides with iodide. The first method is a modification of a literature procedure employing triphenylphosphine and iodine, where purification has been