483287-70-3

Upstream product

• 108943-44-8 (S)-(-)-5-ethyl-δ-valerolactone 
• 483287-63-4 (R,R)-(+)-N-(1-(1-naphthyl)ethyl)-5-hydroxyheptanamide 
• 3301-90-4 6-ethyl-tetrahydro-2H-pyran-2-one 
• 113611-50-0 (S)-(+)-5-hydroxyheptanol 

Relevant academic research and scientific papers

Optical resolution of 5-alkyl-δ-valerolactones and synthesis of optically active 5-fluoroalkanols

Optical resolutions of 5-alkyl-δ-valerolactones were carried out by derivatization to the diastereomeric amides, in which (R)-(+)-1-(1-naphthyl)ethylamine or (S)-(-)-1-phenylethylamine were used as resolving agents. Optically active 5-fluoroalkanols, useful intermediates for fluorinated ferroelectric liquid crystals, were derived from the resolved lactones in four steps without racemization.

Synthesis and properties of ferroelectric liquid crystals derived from 5-alkyl-δ-valerolactones

New homologous FLCs (I-II-n [n=1-4]) derived from optically active 5-alkyl-6-valerolactones were synthesized. Their mesomorphic properties were systematically investigated with respect to their molecular structures, which were different in terms of the le