483341-86-2

Basic information

• Product Name: (1S,4S,6R)-4,6-bis[(N-benzyl)-o-nitrobenzenesulfon-amino]-cyclohex-2-enol
• Synonyms: (1S,4S,6R)-4,6-bis[(N-benzyl)-o-nitrobenzenesulfon-amino]-cyclohex-2-enol
• CAS NO: 483341-86-2
• Molecular Weight: 678.744
• Mol File: 483341-86-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,4S,6R)-4,6-bis[(N-benzyl)-o-nitrobenzenesulfon-amino]-cyclohex-2-enol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4S,6R)-4,6-bis[(N-benzyl)-o-nitrobenzenesulfon-amino]-cyclohex-2-enol(483341-86-2)
• EPA Substance Registry System: (1S,4S,6R)-4,6-bis[(N-benzyl)-o-nitrobenzenesulfon-amino]-cyclohex-2-enol(483341-86-2)

Safety Data

• Hazardous Substances Data: 483341-86-2(Hazardous Substances Data)

Upstream product

• 42060-32-2 N-benzyl-2-nitrobenzenesulfonamide 
• 483341-85-1 (1R,2S,6R)-6-(N-benzyl)-o-nitrobenzenesulfonamino-1,2-di-O-carbonyl-cyclohex-3-ene-1,2-diol 
• 483341-83-9 (3S,4R,5R)-3,4-O-isopropylidene-5-(N-benzyl)-o-nitro-benzensulfon-amino-octa-1,7-diene-3,4-diol 
• 483341-84-0 (1R,2S,6R)-6-(N-benzyl)-o-nitrobenzenesulfonamino-1,2-O-isopropylidene-cyclohex-3-en-1,2-diol 
• 483341-82-8 Benzyl-[(R)-1-((4R,5S)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-but-3-enyl]-amine 
• 100-46-9 benzylamine 

Downstream Products

• 688334-49-8 Acetic acid (1S,4S,6R)-4,6-bis-[benzyl-(2-nitro-benzenesulfonyl)-amino]-cyclohex-2-enyl ester 
• 688334-50-1 (1S,4S,6R)-4,6-bis[(N-benzyl)-o-nitrobenzenesulfon-amino]-1-O-(tert-butyldimethylsilyl)-cyclohex-2-enol 

Relevant articles and documents

Synthesis of orthogonally protected 2-deoxystreptamine stereoisomers

Enantiomerically pure 4,6-diaminocyclohexenols are obtained from carbohydrate derived 1,7-dienes by ring-closing metathesis and palladium catalyzed allylic amination using o-nitrobenzenesulfonylamides as nucleophiles. In the latter reaction the use of a cyclic carbonate as a leaving group proved to be essential to facilitate a smooth substitution. The obtained compounds were converted into orthogonally protected diaminocyclitols, which are stereoisomers of the naturally occurring 2-deoxystreptamine, a constituent of aminoglycoside antibiotics.