483370-11-2Relevant academic research and scientific papers
Biphenyl derivatives as novel dual NK(1)/NK(2)-receptor antagonists.
Mah, Robert,Gerspacher, Marc,von Sprecher, Andreas,Stutz, Stefan,Tschinke, Vincenzo,Anderson, Gary P,Bertrand, Claude,Subramanian, Natarajan,Ball, Howard A
, p. 2065 - 2068 (2007/10/03)
In a continuation of our efforts to simplify the structure of our neurokinin antagonists, a series of substituted biphenyl derivatives has been prepared. Several compounds exhibit potent affinities for both the NK(1) receptor (10nM) and for the NK(2) rec
