484-76-4 Usage
Uses
Used in Pharmaceutical Industry:
OKANIN is used as an antibacterial agent for its ability to effectively combat bacterial infections. Its natural origin and potent antibacterial properties make it a promising candidate for the development of new antibiotics to address the growing issue of antibiotic resistance.
OKANIN is also used as an anti-inflammatory agent for its potential to reduce inflammation and alleviate pain associated with various conditions. Its natural source and anti-inflammatory properties make it a valuable addition to the development of new anti-inflammatory drugs.
Used in Anticancer Applications:
OKANIN is used as an anti-cancer agent, particularly for its ability to target and inhibit the growth of cancer cells. Its natural origin and potent anti-cancer properties make it a promising candidate for the development of novel cancer treatments and therapies.
Used in Cosmetics Industry:
OKANIN, due to its anti-inflammatory and antibacterial properties, can be used in the development of skincare products. It can help in reducing inflammation, soothing irritated skin, and preventing bacterial infections, making it a valuable ingredient for various cosmetic formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 484-76-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 484-76:
(5*4)+(4*8)+(3*4)+(2*7)+(1*6)=84
84 % 10 = 4
So 484-76-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H12O6/c16-10(9-3-6-12(18)15(21)14(9)20)4-1-8-2-5-11(17)13(19)7-8/h1-7,17-21H/b4-1+
484-76-4Relevant academic research and scientific papers
Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers
Hofmann, Emily,Webster, Jonathan,Do, Thuy,Kline, Reid,Snider, Lindsey,Hauser, Quintin,Higginbottom, Grace,Campbell, Austin,Ma, Lili,Paula, Stefan
, p. 578 - 587 (2016/02/09)
In this study, we evaluated the abilities of a series of chalcones to inhibit the activity of the enzyme xanthine oxidase (XO) and to scavenge radicals. 20 mono- and polyhydroxylated chalcone derivatives were synthesized by Claisen-Schmidt condensation reactions and then tested for inhibitory potency against XO, a known generator of reactive oxygen species (ROS). In parallel, the ability of the synthesized chalcones to scavenge a stable radical was determined. Structure-activity relationship analysis in conjunction with molecular docking indicated that the most active XO inhibitors carried a minimum of three hydroxyl groups. Moreover, the most effective radical scavengers had two neighboring hydroxyl groups on at least one of the two phenyl rings. Since it has been proposed previously that XO inhibition and radical scavenging could be useful properties for reduction of ROS-levels in tissue, we determined the chalcones' effects to rescue neurons subjected to ROS-induced stress created by the addition of β-amyloid peptide. Best protection was provided by chalcones that combined good inhibitory potency with high radical scavenging ability in a single molecule, an observation that points to a potential therapeutic value of this compound class.
