484014-15-5Relevant academic research and scientific papers
Design and synthesis of novel χ2-constrained phenylalanine, naphthylalanine, and tryptophan analogues and their use in biologically active melanotropin peptides
Wang, Wei,Cai, Minying,Xiong, Chiyi,Zhang, Junyi,Trivedi, Dev,Hruby, Victor J
, p. 7365 - 7374 (2007/10/03)
A series of novel hydrophobic, bulky χ2-constrained phenylalanine, naphthylalanine, and tryptophan derivatives was designed and synthesized. The key steps involved asymmetric hydrogenations of α-enamides using Burk's DuPHOS-based Rh(I) catalyst
