4841-70-7

Basic information

• Product Name: N-[(Benzyloxy)carbonyl]-L-methionine pentachlorophenyl ester
• Synonyms: N-[(Benzyloxy)carbonyl]-L-methionine pentachlorophenyl ester
• CAS NO: 4841-70-7
• Molecular Formula: C19H16Cl5NO4S
• Molecular Weight: 531.66
• Mol File: 4841-70-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[(Benzyloxy)carbonyl]-L-methionine pentachlorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(Benzyloxy)carbonyl]-L-methionine pentachlorophenyl ester(4841-70-7)
• EPA Substance Registry System: N-[(Benzyloxy)carbonyl]-L-methionine pentachlorophenyl ester(4841-70-7)

Safety Data

• Hazardous Substances Data: 4841-70-7(Hazardous Substances Data)

Upstream product

• 1152-62-1 Cbz-Met-OH 
• 5672-86-6 pentachlorophenyl trifluoroacetate 
• 87-86-5 Pentachlorophenol 

Downstream Products

• 15998-55-7 N-carbobenzoxy-DL-methionylglycine ethyl ester 
• 33857-84-0 N-(benzyloxycarbonyl)-L-methionyl-L-valine methyl ester 

Relevant articles and documents

Kinetic Studies in Peptide Chemistry. Coupling, Racemization, and Evaluation of Methods Useful for Shortening Coupling Time

Kinetic studies were carried out on N-protected methionine and glycylmethionine active esters to determine the racemization rate constants with triethylamine and the coupling rate constants with valine methyl ester.In contrast to cysteine dipeptide active esters, which racemize through an enolization mechanism, the methionine dipeptide active esters racemize through the usual 5(4H)-oxazolone route.The role of sulfur in the side chain is discussed.The time required for coupling a given percentage (e.g., 99 percent) of the amine component can be significantly reduced by using an excess of the active ester.This method is evaluated quantitatively for second-order kinetics.