4842-61-9Relevant articles and documents
Lipase catalysed kinetic resolutions of 3-aryl alkanoic acids
Deasy, Rebecca E.,Brossat, Maude,Moody, Thomas S.,Maguire, Anita R.
experimental part, p. 47 - 61 (2011/04/18)
Hydrolase catalysed kinetic resolutions leading to a series of 3-aryl alkanoic acids (≥94% ee) are described. Hydrolysis of the ethyl esters with a series of hydrolases was undertaken to identify biocatalysts that yield the corresponding acids with excellent enantiopurity in each case. Steric and electronic effects on the efficiency and enantioselectivity of the biocatalytic transformation were also explored.
Synthese Asymetrique. 2. Additions Conjuguees Enantioselectives de Reactifs de Grignard a la Cinnamamide et la Crotonamide derivant du (R)-(-)-N-(2-Fluorobenzyl)-2-Aminobutan-1-ol. Determination de l'exces Diastereomerique au moyen de la RMN de 19F
Brown, Eric,Deroye, Christelle,Huet, Francois,Grumelec, Christelle Le,Touet, Joel
, p. 2227 - 2243 (2007/10/03)
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Efficient Method for the Total Asymmetric Synthesis of the Isomers of β-Methyltyrosine
Nicolas, Ernesto,Russell, K. C.,Knollenberg, J.,Hruby, Victor J.
, p. 7565 - 7571 (2007/10/02)
α-Amino acids modified at the β-carbon atom can provide topographical constraints when incorporated into a peptide.Such modifications can modulate the physical, chemical, and biological properties of the compound.In order to properly evaluate the effect o