484653-06-7Relevant articles and documents
Synthesis and preliminary pharmacological evaluation of new (+/-) 1,4-naphthoquinones structurally related to lapachol.
da Silva, Alcides J M,Buarque, Camilla D,Brito, Flavia V,Aurelian, Laure,Macedo, Luciana F,Malkas, Linda H,Hickey, Robert J,Lopes, Daniele V S,Noel, Francois,Murakami, Yugo L B,Silva, Noelson M V,Melo, Paulo A,Caruso, Rodrigo R B,Castro, Newton G,Costa, Paulo R R
, p. 2731 - 2738 (2002)
Seven new 1,4-naphthoquinones structurally related to lapachol were synthesized from lawsone and oxygenated arylmercurials. These compounds can also be seen as pterocarpan derivatives where the A-ring was substituted by the 1,4-naphthoquinone nucleus. Pha
