484672-06-2

Upstream product

• 484671-90-1 Imidazole-1-carboxylic acid (E)-(2R,3S,7R,9R,10R,11R,13R)-10-((2S,3R,4S,6R)-3-benzoyloxy-4-dimethylamino-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-9-methoxy-5,7,9,11,13-pentamethyl-6,12,14-trioxo-oxacyclotetradec-4-en-3-yl ester 
• 173838-44-3 [4-(1H-imidazo[4,5-b]pyridin-1-yl)butyl]amine 
• 484671-87-6 Benzoic acid (2S,3R,4S,6R)-4-dimethylamino-2-((3R,4S,5S,6R,7R,9R,10S,11S,12R,13R,14R)-14-ethyl-4,10,12-trihydroxy-13-methanesulfonyloxy-7-methoxy-3,5,7,9,11-pentamethyl-2-oxo-oxacyclotetradec-6-yloxy)-6-methyl-tetrahydro-pyran-3-yl ester 
• 791103-02-1 Benzoic acid (2S,3R,4S,6R)-4-dimethylamino-2-((3R,5R,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-12-hydroxy-13-methanesulfonyloxy-7-methoxy-3,5,7,9,11-pentamethyl-2,4,10-trioxo-oxacyclotetradec-6-yloxy)-6-methyl-tetrahydro-pyran-3-yl ester 
• 484671-89-8 Benzoic acid (2S,3R,4S,6R)-4-dimethylamino-2-((E)-(3R,5R,6R,7R,9R,13S,14R)-14-ethyl-13-hydroxy-7-methoxy-3,5,7,9,11-pentamethyl-2,4,10-trioxo-oxacyclotetradec-11-en-6-yloxy)-6-methyl-tetrahydro-pyran-3-yl ester 
• 484671-86-5 C₅₅H₈₃NO₁₇S 
• 484671-85-4 C₅₄H₈₁NO₁₅ 
• 484670-62-4 C₅₅H₈₁NO₁₄ 
• 484671-84-3 C₅₄H₇₉NO₁₅ 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of C12 des-methyl ketolides

Synthesis of C12 des-methyl ketolide is developed featuring an intramolecular epoxide formation/elimination process to establish the C12 stereocenter. These ketolides are potent against several key respiratory pathogens, including er

PYRIDYL SUBSTITUTED KETOLIDE ANTIBIOTICS

Antimicrobial macrolide and ketolide compounds are provided having formulas (XII), as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.